Protein Engineering 2022 : Bioengineering Special Issue: Protein Engineering in Tolerogenic Antigen Delivery

Dear Colleagues,

The development of safe and effective antigen-specific therapies is needed to prevent or treat patients with autoimmune diseases, allergies, and drug hypersensitivities. Novel protein engineering strategies and antigen delivery platforms have emerged as powerful tools to modulate immune responses in an antigen-specific manner. This Special Issue on "Protein Engineering in Tolerogenic Antigen Delivery" will focus on strategies to deliver antigen for the induction of prophylactic or therapeutic tolerance in various settings. Topics of interest for this Special Issue include but are not limited to antigen-encoding DNA vaccines, peptide or whole antigen delivery, antigen-loaded targeting antibodies, epitopes loaded into relevant carriers, antigen co-delivery with immunomodulators, antigen targeted delivery to antigen presenting cells (APCs), autoantigen loaded tolerogenic APC vaccines, targeting of specific sites such as the liver, lymphatics or mucosa. Original research articles and review articles are welcome.

Please contact Sophie Wang ([email protected]) if you have any questions.

Dr. Shijie Cao
Dr. Novalia Pishesha
Guest Editors